GUCY1A1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GUCY1A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,979 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GUCY1A1-associated proteins across cancer lineages are GUCY1B1, PDLIM7, and PRKG1. Each is linked with GUCY1A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both GUCY1A1-to-partner and partner-to-GUCY1A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GUCY1A1 versus GUCY1B1 in OV, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCY1A1→partner) and Y-score (partner→GUCY1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVGUCY1B1 →+0.460+1.136<.001<.001310
OVPDLIM7 →+0.611+1.078<.001<.00139
CCRCCPRKG1 →+0.657+0.903<.001<.00139
COADRSU1 →+0.394+0.847<.001<.00139
GBMSVIL →+0.408+0.696<.001<.00138
CCRCCVCL →+0.466+0.802<.001.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,979 associations by consensus.

GUCY1A1 vs GUCY1B1 — OV

Per-sample scatter of GUCY1A1 vs GUCY1B1 in OV (Pearson r = 0.69).

Explore this scatter interactively →

Exploration