GUCY1A1

Across TCGA cell cohorts, GUCY1A1 RNA expression is significantly associated with the RNA expression of many other genes, with 5,866 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GUCY1A1-associated genes across cancer lineages are GUCY1B1, CTSO, and MAP9. Each is linked with GUCY1A1 in more than 12 cancer types. Because this analysis shows association rather than direction, both GUCY1A1-to-partner and partner-to-GUCY1A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GUCY1A1 versus GUCY1B1 in KIDNEY, with a Pearson correlation of 0.89.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCY1A1→partner) and Y-score (partner→GUCY1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	GUCY1B1 →	+2.248	+2.437	<.001	<.001	3	13
BLOOD_Myeloma	CTSO →	+2.433	+2.724	<.001	<.001	3	5
STOMACH	MAP9 →	+2.172	+2.052	<.001	.001	3	5
LIVER	CTTNBP2 →	+1.554	+2.181	.002	.004	2	5
CNS	C3orf80 →	+1.118	+1.032	<.001	<.001	3	3
BLOOD_Leukemia	ZNF737 →	+1.505	+1.406	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,866 associations by consensus.

GUCY1A1 vs GUCY1B1 — KIDNEY

Explore this scatter interactively →