GUCY1A1

Across TCGA cell cohorts, GUCY1A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,519 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GUCY1A1-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Plasminogen activation, and Regulation of G1/S transition of mitotic cell cycle. Each is linked with GUCY1A1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GUCY1A1-to-partner and partner-to-GUCY1A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by GUCY1A1-low versus GUCY1A1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCY1A1→partner) and Y-score (partner→GUCY1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of nucleotide-excision repair →	+0.086	+1.132	.005	.005	3	8
LIVER	Plasminogen activation →	-0.412	-2.077	.003	.006	3	7
STOMACH	Regulation of G1/S transition of mitotic cell cycle →	+0.091	+2.194	<.001	.006	3	7
LIVER	ATP synthesis coupled electron transport →	+0.086	+2.434	.004	<.001	2	8
LIVER	Mitochondrial ATP synthesis coupled electron transport →	+0.086	+2.434	.004	<.001	2	8
CNS	Regulation of DNA-templated transcription elongation →	+0.040	+0.885	.005	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,519 associations by consensus.

Regulation of nucleotide-excision repair by GUCY1A1 expression — OESOPHAGUS

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