GUCA1B

Across TCGA pan-cancer cohorts, GUCA1B Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated GUCA1B data layer compared with 22 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher GUCA1B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GUCA1B expression acts as an unfavorable survival marker.

LUAD, LGG, and ACC are the cancer types where GUCA1B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.252	0.687	<.001	30	view →
LGG	OS	Median	All	0.147	0.811	<.001	12	view →
ACC	OS	Median	All	0.118	0.624	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

GUCA1B–LUAD (OS)

Open the LUAD breakdown →