GUCA1A

Across TCGA patient cohorts, GUCA1A RNA expression is significantly associated with the go_rna of many other GO terms, with 7,116 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GUCA1A-associated GO terms across cancer lineages are Chondrocyte development, Collagen fibril organization, and Collagen metabolic process. Each is linked with GUCA1A in more than 19 cancer types. Because this analysis shows association rather than direction, both GUCA1A-to-partner and partner-to-GUCA1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chondrocyte development grouped by GUCA1A-low versus GUCA1A-high in OV.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCA1A→partner) and Y-score (partner→GUCA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	Chondrocyte development →	+0.073	+0.166	<.001	<.001	3	20
ESCA	Collagen fibril organization →	+0.100	+0.459	<.001	<.001	3	20
ESCA	Collagen metabolic process →	+0.067	+0.375	<.001	<.001	3	20
ESCA	Regulation of chondrocyte differentiation →	+0.048	+0.393	<.001	<.001	3	19
ESCA	Positive regulation of vasculature development →	+0.056	+0.437	<.001	<.001	3	19
ESCA	Endoderm formation →	+0.077	+0.337	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,116 associations by consensus.

Chondrocyte development by GUCA1A expression — OV

Explore this box plot interactively →