GUCA1A

Across TCGA patient cohorts, GUCA1A protein abundance is significantly associated with the RNA expression of many other genes, with 2,349 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GUCA1A-associated genes across cancer lineages are ERBB2, ADAMTS7, and GRASLND. Each is linked with GUCA1A in more than 1 cancer types. Because this analysis shows association rather than direction, both GUCA1A-to-partner and partner-to-GUCA1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GUCA1A versus ERBB2 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCA1A→partner) and Y-score (partner→GUCA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ERBB2 →	+0.922	+0.617	<.001	<.001	3	2
GBM	ADAMTS7 →	-0.676	-0.573	<.001	<.001	3	2
GBM	GRASLND →	-0.650	-0.446	.001	.001	3	2
GBM	KCNK1 →	-1.248	-0.426	<.001	.001	3	2
GBM	FAM89A →	-0.560	-0.317	.005	.004	3	2
GBM	NANOGP9 →	+0.244	+0.383	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,349 associations by consensus.

GUCA1A vs ERBB2 — GBM

Explore this scatter interactively →