GUCA1A

Across TCGA patient cohorts, GUCA1A mutation is significantly associated with the RNA expression of many other genes, with 814 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GUCA1A-associated genes across cancer lineages are RNA5SP426, RNU6-983P, and MIR876. Each is linked with GUCA1A in more than 3 cancer types. Because this analysis shows association rather than direction, both GUCA1A-to-partner and partner-to-GUCA1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP426 grouped by GUCA1A-low versus GUCA1A-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCA1A→partner) and Y-score (partner→GUCA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNA5SP426 →	+0.895	+4.520	<.001	.005	3	4
BRCA	RNU6-983P →	+0.231	+7.471	<.001	.008	3	2
STAD	MIR876 →	+0.679	+5.070	<.001	.004	3	2
STAD	RN7SKP53 →	+0.218	+4.290	.003	.008	3	2
STAD	RN7SL215P →	+0.579	+4.254	<.001	.008	3	2
STAD	MIR4289 →	+0.622	+4.798	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 814 associations by consensus.

RNA5SP426 by GUCA1A expression — STAD

Explore this box plot interactively →