GUCA1A

RNA expression — cross-omics
Cross-omicsRNA → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GUCA1A RNA expression is significantly associated with the RNA expression of many other genes, with 1,837 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GUCA1A-associated genes across cancer lineages are KRTAP5-6, CUL9, and SHCBP1L. Each is linked with GUCA1A in more than 2 cancer types. Because this analysis shows association rather than direction, both GUCA1A-to-partner and partner-to-GUCA1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GUCA1A versus KRTAP5-6 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.40.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCA1A→partner) and Y-score (partner→GUCA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTKRTAP5-6 →+0.114+0.054<.001<.00133
BREASTCUL9 →+0.791+0.014.001<.00132
URINARY_TRACTSHCBP1L →+0.034+0.023.006<.00132
SKINOR6K6 →+0.007+0.715.007<.00132
CNSMYOG →+0.587+1.256<.001<.00132
CNSRGR →+0.156+1.184.005<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,837 associations by consensus.

GUCA1A vs KRTAP5-6 — UPPER_AERODIGESTIVE_TRACT

Per-sample scatter of GUCA1A vs KRTAP5-6 in UPPER_AERODIGESTIVE_TRACT (Pearson r = 0.40).

Explore this scatter interactively →

Exploration