GTSF1L

Across TCGA patient cohorts, GTSF1L mutation is significantly associated with the RNA expression of many other genes, with 149 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTSF1L-associated genes across cancer lineages are SNRPGP17, RNA5SP396, and RNU6-1060P. Each is linked with GTSF1L in more than 1 cancer types. Because this analysis shows association rather than direction, both GTSF1L-to-partner and partner-to-GTSF1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPGP17 grouped by GTSF1L-low versus GTSF1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTSF1L→partner) and Y-score (partner→GTSF1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNRPGP17 →	+0.368	+2.463	<.001	.008	3	2
UCEC	RNA5SP396 →	+0.623	+3.262	<.001	.006	3	2
LUSC	RNU6-1060P →	+0.356	+5.081	<.001	.004	3	2
UCEC	LYPLA1P1 →	+0.097	+4.827	<.001	<.001	3	2
BLCA	RPL37P21 →	+0.124	+7.640	<.001	.009	3	2
BLCA	RNA5SP138 →	+0.274	+7.640	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 149 associations by consensus.

SNRPGP17 by GTSF1L expression — UCEC

Explore this box plot interactively →