GTSF1L

Across TCGA cell cohorts, GTSF1L RNA expression is significantly associated with the go_rna of many other GO terms, with 1,339 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GTSF1L-associated GO terms across cancer lineages are T-helper 2 cell differentiation, Spliceosomal complex assembly, and Nuclear transport. Each is linked with GTSF1L in more than 3 cancer types. Because this analysis shows association rather than direction, both GTSF1L-to-partner and partner-to-GTSF1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T-helper 2 cell differentiation grouped by GTSF1L-low versus GTSF1L-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTSF1L→partner) and Y-score (partner→GTSF1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	T-helper 2 cell differentiation →	-0.064	-0.229	.005	.009	3	4
LUNG_NSCLC_LUAD	Spliceosomal complex assembly →	+0.065	+0.019	<.001	.005	3	3
LUNG_NSCLC_LUAD	Nuclear transport →	+0.050	+0.018	.001	.008	3	3
LUNG_NSCLC_LUAD	Nucleocytoplasmic transport →	+0.050	+0.018	.001	.008	3	3
LUNG_NSCLC_LUAD	Protein-RNA complex organization →	+0.040	+0.014	.008	.002	3	3
SOFT_TISSUE	Pattern recognition receptor signaling pathway →	+0.060	+0.054	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,339 associations by consensus.

T-helper 2 cell differentiation by GTSF1L expression — BLOOD_Leukemia

Explore this box plot interactively →