GTSF1

Across TCGA patient cohorts, GTSF1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,442 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTSF1-associated genes across cancer lineages are IGKJ1, MAGEA10, and CTAG2. Each is linked with GTSF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GTSF1-to-partner and partner-to-GTSF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTSF1 versus IGKJ1 in UCEC, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTSF1→partner) and Y-score (partner→GTSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKJ1 →	+4.503	+2.603	<.001	.003	3	3
UCEC	MAGEA10 →	+2.350	+2.503	.006	<.001	3	2
LSCC	CTAG2 →	+2.745	+1.559	<.001	<.001	3	2
HNSC	H2BC1 →	+0.502	+0.933	.009	<.001	3	2
BRCA	SHMT1 →	-0.905	-1.307	.002	.007	3	2
HNSC	MAGEA1 →	+2.184	+1.162	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,442 associations by consensus.

GTSF1 vs IGKJ1 — UCEC

Explore this scatter interactively →