GTSF1

Across TCGA cell cohorts, GTSF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 883 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GTSF1-associated GO terms across cancer lineages are Secondary piRNA processing, Regulation of RNA polymerase II transcription preinitiation complex assembly, and Regulation of type B pancreatic cell apoptotic process. Each is linked with GTSF1 in more than 15 cancer types. Because this analysis shows association rather than direction, both GTSF1-to-partner and partner-to-GTSF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Secondary piRNA processing grouped by GTSF1-low versus GTSF1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTSF1→partner) and Y-score (partner→GTSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Secondary piRNA processing →	+2.158	+6.783	<.001	<.001	3	16
LARGE_INTESTINE	Regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.117	+0.137	.002	.009	2	5
OESOPHAGUS	Regulation of type B pancreatic cell apoptotic process →	+0.117	+3.966	.009	.001	3	4
LARGE_INTESTINE	Regulation of cell fate specification →	+0.102	+0.114	.001	.007	2	4
BLOOD_Leukemia	Cholesterol transport →	+0.059	+2.877	<.001	.003	3	3
BLOOD_Leukemia	Stress-induced premature senescence →	-0.064	-2.112	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 883 associations by consensus.

Secondary piRNA processing by GTSF1 expression — LIVER

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