GTSCR1

Across TCGA pan-cancer cohorts, GTSCR1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of GTSCR1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where GTSCR1 RNA is repressed in tumor relative to normal tissue. In most cancer types GTSCR1 is over-expressed in tumor, although a few such as LIHC and PAAD show the opposite, repressed pattern.

LIHC, BRCA, and STAD are the cancer types where GTSCR1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GTSCR1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	−0.202	<.001	5	view →
BRCA	Female	II,III,IV	+0.126	<.001	4	view →
STAD	Female	All	+0.324	.010	2	view →
PAAD	Male	All	−0.200	.009	2	view →
KIRC	All	All	+0.056	.011	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

GTSCR1–LIHC

Open the LIHC breakdown →