GTPBP8

Across TCGA patient cohorts, GTPBP8 protein abundance is significantly associated with the RNA expression of many other genes, with 4,121 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GTPBP8-associated genes across cancer lineages are ITFG1, FBP1, and SLC25A30. Each is linked with GTPBP8 in more than 2 cancer types. Because this analysis shows association rather than direction, both GTPBP8-to-partner and partner-to-GTPBP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTPBP8 versus ITFG1 in LUAD, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP8→partner) and Y-score (partner→GTPBP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ITFG1 →	-0.647	-0.574	<.001	.001	3	3
BRCA	FBP1 →	-1.866	-0.469	.003	.005	3	3
LUAD	SLC25A30 →	-0.534	-0.537	<.001	<.001	3	3
LUAD	CD40 →	-0.766	-0.350	<.001	.002	3	2
LUAD	PHKB →	-0.542	-0.417	.001	.004	3	2
LUAD	LONP2 →	-0.543	-0.514	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,121 associations by consensus.

GTPBP8 vs ITFG1 — LUAD

Explore this scatter interactively →