GTPBP8

Across TCGA patient cohorts, GTPBP8 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTPBP8-associated genes across cancer lineages are Epithelial cells, Keratinocytes, and Mesangial cells. Each is linked with GTPBP8 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTPBP8-to-partner and partner-to-GTPBP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cells grouped by GTPBP8-low versus GTPBP8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP8→partner) and Y-score (partner→GTPBP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Epithelial cells →	-0.114	-2.989	.001	.035	3	1
UCEC	Keratinocytes →	-0.015	-3.330	.030	.006	3	1
UCEC	Mesangial cells →	-0.060	-3.448	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Epithelial cells by GTPBP8 expression — UCEC

Explore this box plot interactively →