GTPBP4

Across TCGA patient cohorts, GTPBP4 protein abundance is significantly associated with the RNA expression of many other genes, with 19,755 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GTPBP4-associated genes across cancer lineages are HROB, ABCA8, and HSPD1. Each is linked with GTPBP4 in more than 7 cancer types. Because this analysis shows association rather than direction, both GTPBP4-to-partner and partner-to-GTPBP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTPBP4 versus HROB in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP4→partner) and Y-score (partner→GTPBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HROB →	+0.951	+0.323	<.001	<.001	3	8
OV	ABCA8 →	-0.899	-0.337	<.001	<.001	3	8
UCEC	HSPD1 →	+0.715	+0.278	.002	<.001	3	8
HNSC	CENPH →	+0.816	+0.291	<.001	<.001	3	8
UCEC	CDT1 →	+1.041	+0.305	<.001	<.001	3	8
HNSC	NME1 →	+0.773	+0.294	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,755 associations by consensus.

GTPBP4 vs HROB — HNSC

Explore this scatter interactively →