GTPBP4

Across TCGA patient cohorts, GTPBP4 mutation is significantly associated with the RNA expression of many other genes, with 2,035 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTPBP4-associated genes across cancer lineages are FABP5P4, TRGV11, and SNORD116-22. Each is linked with GTPBP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both GTPBP4-to-partner and partner-to-GTPBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FABP5P4 grouped by GTPBP4-low versus GTPBP4-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP4→partner) and Y-score (partner→GTPBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	FABP5P4 →	+0.287	+5.925	<.001	.002	3	3
CESC	TRGV11 →	+0.085	+3.411	<.001	.009	3	3
SKCM	SNORD116-22 →	+0.336	+3.684	<.001	<.001	3	2
SKCM	OR4K11P →	+0.030	+4.025	<.001	.007	3	2
SKCM	RNA5SP432 →	+0.211	+2.855	.001	.001	3	2
READ	RNU6-784P →	+0.430	+6.257	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,035 associations by consensus.

FABP5P4 by GTPBP4 expression — READ

Explore this box plot interactively →