GTPBP4

Across TCGA patient cohorts, GTPBP4 mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTPBP4-associated genes across cancer lineages are Eosinophils, Adipocytes, and HSC. Each is linked with GTPBP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTPBP4-to-partner and partner-to-GTPBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophils grouped by GTPBP4-low versus GTPBP4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP4→partner) and Y-score (partner→GTPBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Eosinophils →	+0.067	+1.930	<.001	.040	3	2
UCEC	Adipocytes →	+0.019	+1.301	.001	.039	3	2
UCEC	HSC →	+0.081	+1.815	.031	.016	3	2
LUSC	Macrophages →	+0.058	+2.866	.007	.042	3	1
READ	CD4+ memory T-cells →	+0.014	+4.242	.008	.024	3	1
UCEC	CD8+ naive T-cells →	+0.025	+2.491	.006	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Eosinophils by GTPBP4 expression — SKCM

Explore this box plot interactively →