GTPBP4

Across TCGA cell cohorts, GTPBP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,483 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GTPBP4-associated GO terms across cancer lineages are Maturation of SSU-rRNA, 'de novo' IMP biosynthetic process, and Mitochondrial RNA 3'-end processing. Each is linked with GTPBP4 in more than 15 cancer types. Because this analysis shows association rather than direction, both GTPBP4-to-partner and partner-to-GTPBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by GTPBP4-low versus GTPBP4-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP4→partner) and Y-score (partner→GTPBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Maturation of SSU-rRNA →	+0.120	+1.211	<.001	<.001	3	16
URINARY_TRACT	'de novo' IMP biosynthetic process →	+0.160	+0.895	<.001	<.001	3	16
LIVER	Mitochondrial RNA 3'-end processing →	+0.097	+0.776	.003	.003	3	16
URINARY_TRACT	IMP metabolic process →	+0.119	+0.793	<.001	<.001	3	15
OESOPHAGUS	'de novo' cotranslational protein folding →	+0.161	+1.052	<.001	<.001	3	15
URINARY_TRACT	IMP biosynthetic process →	+0.219	+1.019	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,483 associations by consensus.

Maturation of SSU-rRNA by GTPBP4 expression — BLOOD_Lymphoma

Explore this box plot interactively →