GTPBP2

Across TCGA patient cohorts, GTPBP2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,210 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GTPBP2-associated genes across cancer lineages are MYBL2, HJURP, and CDCA5. Each is linked with GTPBP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GTPBP2-to-partner and partner-to-GTPBP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTPBP2 versus MYBL2 in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP2→partner) and Y-score (partner→GTPBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYBL2 →	+1.409	+0.327	<.001	<.001	3	5
BRCA	HJURP →	+1.067	+0.391	<.001	<.001	3	4
BRCA	CDCA5 →	+0.960	+0.401	<.001	<.001	3	4
LUAD	MELK →	+1.171	+0.330	<.001	<.001	3	4
BRCA	KIF18B →	+1.035	+0.373	<.001	<.001	3	4
LSCC	MCM10 →	+0.911	+0.305	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,210 associations by consensus.

GTPBP2 vs MYBL2 — BRCA

Explore this scatter interactively →