GTPBP2

Across TCGA patient cohorts, GTPBP2 mutation is significantly associated with the RNA expression of many other genes, with 2,290 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTPBP2-associated genes across cancer lineages are RN7SL14P, MBD3L3, and IMP3P2. Each is linked with GTPBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTPBP2-to-partner and partner-to-GTPBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL14P grouped by GTPBP2-low versus GTPBP2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP2→partner) and Y-score (partner→GTPBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL14P →	+0.155	+5.317	<.001	.006	3	2
CESC	MBD3L3 →	+0.421	+5.144	<.001	.003	3	2
UCEC	IMP3P2 →	+0.202	+1.499	<.001	.004	3	2
UCEC	RAB5CP2 →	+0.161	+1.739	.001	.002	3	2
BLCA	MIR6891 →	+0.605	+3.160	<.001	.003	3	2
SKCM	RNA5SP321 →	+0.217	+5.212	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,290 associations by consensus.

RN7SL14P by GTPBP2 expression — BRCA

Explore this box plot interactively →