GTPBP10

Across TCGA patient cohorts, GTPBP10 mutation is significantly associated with the RNA expression of many other genes, with 2,027 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTPBP10-associated genes across cancer lineages are RNU6-923P, RNU7-136P, and MARK2P6. Each is linked with GTPBP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTPBP10-to-partner and partner-to-GTPBP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-923P grouped by GTPBP10-low versus GTPBP10-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP10→partner) and Y-score (partner→GTPBP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-923P →	+0.564	+4.418	<.001	.006	3	2
LUSC	RNU7-136P →	+0.603	+5.337	<.001	.006	3	2
SKCM	MARK2P6 →	+0.059	+3.243	.002	.009	3	2
UCEC	IL9 →	+0.075	+2.063	.004	.006	3	2
UCEC	YTHDF3-AS1 →	+0.629	+2.141	<.001	.003	3	1
UCEC	DOC2B →	-1.161	-2.087	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,027 associations by consensus.

RNU6-923P by GTPBP10 expression — LUAD

Explore this box plot interactively →