GTPBP10

Across TCGA cell cohorts, GTPBP10 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,942 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GTPBP10-associated GO terms across cancer lineages are tRNA dihydrouridine synthesis, Mitochondrial large ribosomal subunit assembly, and Mitochondrial RNA modification. Each is linked with GTPBP10 in more than 13 cancer types. Because this analysis shows association rather than direction, both GTPBP10-to-partner and partner-to-GTPBP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA dihydrouridine synthesis grouped by GTPBP10-low versus GTPBP10-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP10→partner) and Y-score (partner→GTPBP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	tRNA dihydrouridine synthesis →	+0.097	+0.612	.008	.008	3	14
BLOOD_Myeloma	Mitochondrial large ribosomal subunit assembly →	+0.124	+0.716	.001	.001	3	12
SOFT_TISSUE	Mitochondrial RNA modification →	+0.106	+0.907	<.001	<.001	3	11
BLOOD_Myeloma	Ribosomal large subunit assembly →	+0.107	+0.768	<.001	<.001	3	11
BLOOD_Leukemia	Telomere maintenance via telomerase →	+0.063	+0.334	<.001	.009	3	10
SOFT_TISSUE	Regulation of stress granule assembly →	+0.091	+0.599	<.001	.006	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,942 associations by consensus.

tRNA dihydrouridine synthesis by GTPBP10 expression — KIDNEY

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