GTF3C6

Across TCGA pan-cancer cohorts, GTF3C6 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GTF3C6 data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher GTF3C6 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated GTF3C6 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, LSCC, and PDAC are the cancer types where GTF3C6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	0.931	0.589	.021	7	view →
LSCC	OS	Tertile	All	0.919	0.677	.021	3	view →
PDAC	OS	Median	III,IV	0.833	0.431	.018	2	view →
CCRCC	DFS	Median	All	0.588	0.857	.024	2	view →
HNSC	OS	Median	III,IV	1.000	0.945	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

GTF3C6–LUAD (OS)

Open the LUAD breakdown →