GTF3C5

Across TCGA patient cohorts, GTF3C5 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,498 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF3C5-associated proteins across cancer lineages are GTF3C4, WDR5, and EHMT1. Each is linked with GTF3C5 in more than 8 cancer types. Because this analysis shows association rather than direction, both GTF3C5-to-partner and partner-to-GTF3C5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF3C5 versus GTF3C4 in LSCC, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C5→partner) and Y-score (partner→GTF3C5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GTF3C4 →	+0.398	+0.750	<.001	<.001	3	9
LSCC	WDR5 →	+0.284	+0.630	<.001	<.001	3	9
COAD	EHMT1 →	+0.512	+0.790	<.001	<.001	3	8
GBM	SSRP1 →	+0.578	+0.387	<.001	<.001	3	7
LUAD	RPL12_S38 →	+1.012	+0.408	<.001	<.001	3	7
BRCA	ATAD2 →	+0.549	+0.540	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,498 associations by consensus.

GTF3C5 vs GTF3C4 — LSCC

Explore this scatter interactively →