GTF3C5

Across TCGA patient cohorts, GTF3C5 mutation is significantly associated with the RNA expression of many other genes, with 1,980 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTF3C5-associated genes across cancer lineages are OR5D3P, ETDB, and VPS25P1. Each is linked with GTF3C5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF3C5-to-partner and partner-to-GTF3C5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5D3P grouped by GTF3C5-low versus GTF3C5-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C5→partner) and Y-score (partner→GTF3C5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR5D3P →	+0.066	+5.332	<.001	.002	3	2
COAD	ETDB →	+0.132	+4.418	<.001	.008	3	2
COAD	VPS25P1 →	+0.226	+4.107	<.001	.005	3	2
COAD	RPL39P39 →	+0.441	+4.242	.005	.003	3	2
COAD	UBL5P3 →	+0.294	+4.308	<.001	.009	3	2
COAD	CKS1BP5 →	+0.159	+5.332	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,980 associations by consensus.

OR5D3P by GTF3C5 expression — COAD

Explore this box plot interactively →