GTF3C5

Across TCGA cell cohorts, GTF3C5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,430 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GTF3C5-associated GO terms across cancer lineages are RNA export from nucleus, Regulation of chromatin organization, and Regulation of DNA-templated DNA replication. Each is linked with GTF3C5 in more than 15 cancer types. Because this analysis shows association rather than direction, both GTF3C5-to-partner and partner-to-GTF3C5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA export from nucleus grouped by GTF3C5-low versus GTF3C5-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C5→partner) and Y-score (partner→GTF3C5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	RNA export from nucleus →	+0.124	+0.881	<.001	.002	3	16
SOFT_TISSUE	Regulation of chromatin organization →	+0.096	+1.056	<.001	<.001	3	16
BONE	Regulation of DNA-templated DNA replication →	+0.178	+1.064	<.001	<.001	3	16
BONE	Positive regulation of DNA-templated DNA replication →	+0.148	+0.752	<.001	<.001	3	15
URINARY_TRACT	CTP salvage →	+0.141	+0.642	<.001	.001	3	15
LUNG_NSCLC_LUSC	Nucleic acid transport →	+0.109	+0.864	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,430 associations by consensus.

RNA export from nucleus by GTF3C5 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →