GTF3C4

Across TCGA patient cohorts, GTF3C4 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,144 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF3C4-associated proteins across cancer lineages are BRD3, FUBP3, and PRPF4. Each is linked with GTF3C4 in more than 8 cancer types. Because this analysis shows association rather than direction, both GTF3C4-to-partner and partner-to-GTF3C4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF3C4 versus BRD3 in GBM, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C4→partner) and Y-score (partner→GTF3C4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BRD3 →	+0.360	+0.447	<.001	<.001	3	9
LSCC	FUBP3 →	+0.232	+0.809	<.001	<.001	3	8
GBM	PRPF4 →	+0.422	+0.509	<.001	<.001	3	8
GBM	RBM39 →	+0.230	+0.365	<.001	<.001	3	7
COAD	EHMT1 →	+0.288	+0.464	.001	<.001	3	7
GBM	SET →	+0.472	+0.531	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,144 associations by consensus.

GTF3C4 vs BRD3 — GBM

Explore this scatter interactively →