GTF3C4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GTF3C4 protein abundance is significantly associated with the RNA expression of many other genes, with 19,144 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF3C4-associated genes across cancer lineages are QSOX2, LIN9, and REXO4. Each is linked with GTF3C4 in more than 8 cancer types. Because this analysis shows association rather than direction, both GTF3C4-to-partner and partner-to-GTF3C4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF3C4 versus QSOX2 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C4→partner) and Y-score (partner→GTF3C4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAQSOX2 →+0.793+0.293<.001<.00139
OVLIN9 →+0.702+0.352<.001<.00139
HNSCREXO4 →+0.779+0.315.001<.00139
HNSCGTF3C5 →+0.755+0.246<.001<.00139
HNSCENTR1 →+0.862+0.237<.001<.00139
HNSCWDR5 →+0.786+0.290<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,144 associations by consensus.

GTF3C4 vs QSOX2 — BRCA

Per-sample scatter of GTF3C4 vs QSOX2 in BRCA (Pearson r = 0.41).

Explore this scatter interactively →

Exploration