GTF3C4

Across TCGA patient cohorts, GTF3C4 mutation is significantly associated with the RNA expression of many other genes, with 2,410 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTF3C4-associated genes across cancer lineages are OSBPL9P5, LINC02559, and NOX3. Each is linked with GTF3C4 in more than 2 cancer types. Because this analysis shows association rather than direction, both GTF3C4-to-partner and partner-to-GTF3C4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OSBPL9P5 grouped by GTF3C4-low versus GTF3C4-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C4→partner) and Y-score (partner→GTF3C4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	OSBPL9P5 →	+0.227	+5.321	<.001	.002	3	3
CESC	LINC02559 →	+1.329	+5.342	<.001	.002	3	2
SKCM	NOX3 →	+0.166	+2.511	<.001	.007	3	2
UCEC	ARF4P1 →	+0.551	+2.991	<.001	<.001	3	2
UCEC	H2AC12 →	+0.573	+1.828	<.001	.002	3	2
UCEC	RNA5SP412 →	+0.624	+2.426	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,410 associations by consensus.

OSBPL9P5 by GTF3C4 expression — LUSC

Explore this box plot interactively →