GTF3C4

Across TCGA cell cohorts, GTF3C4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,970 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GTF3C4-associated GO terms across cancer lineages are DNA-templated transcription initiation, Nucleic acid transport, and RNA transport. Each is linked with GTF3C4 in more than 19 cancer types. Because this analysis shows association rather than direction, both GTF3C4-to-partner and partner-to-GTF3C4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by GTF3C4-low versus GTF3C4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C4→partner) and Y-score (partner→GTF3C4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.081	+1.066	<.001	<.001	3	20
STOMACH	Nucleic acid transport →	+0.120	+0.992	<.001	<.001	3	19
STOMACH	RNA transport →	+0.120	+0.992	<.001	<.001	3	19
STOMACH	Establishment of RNA localization →	+0.116	+1.032	<.001	<.001	3	19
BONE	RNA export from nucleus →	+0.135	+0.863	<.001	<.001	3	19
LUNG_SCLC	Regulation of chromatin organization →	+0.115	+0.629	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,970 associations by consensus.

DNA-templated transcription initiation by GTF3C4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →