GTF3C3

Across TCGA patient cohorts, GTF3C3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,116 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF3C3-associated genes across cancer lineages are FCGR2B, FLI1, and RMI2. Each is linked with GTF3C3 in more than 7 cancer types. Because this analysis shows association rather than direction, both GTF3C3-to-partner and partner-to-GTF3C3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF3C3 versus FCGR2B in COAD, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C3→partner) and Y-score (partner→GTF3C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FCGR2B →	-0.975	-0.194	<.001	.001	3	8
LSCC	FLI1 →	-0.708	-0.274	<.001	<.001	3	8
HNSC	RMI2 →	+0.920	+0.324	<.001	<.001	3	8
LSCC	TMEM97 →	+1.218	+0.340	<.001	<.001	3	7
GBM	FOLR2 →	-0.982	-0.190	<.001	<.001	3	7
UCEC	LINC01480 →	-1.326	-0.140	.003	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,116 associations by consensus.

GTF3C3 vs FCGR2B — COAD

Explore this scatter interactively →