GTF3C2

Across TCGA patient cohorts, GTF3C2 mutation is significantly associated with the RNA expression of many other genes, with 3,146 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTF3C2-associated genes across cancer lineages are BCAS2, RPF1, and LIAS. Each is linked with GTF3C2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GTF3C2-to-partner and partner-to-GTF3C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCAS2 grouped by GTF3C2-low versus GTF3C2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C2→partner) and Y-score (partner→GTF3C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BCAS2 →	+0.488	+1.857	<.001	<.001	3	3
COAD	RPF1 →	+0.490	+3.210	.005	.009	3	3
UCEC	LIAS →	+0.336	+2.141	.001	.002	3	3
UCEC	PARP2 →	+0.498	+2.807	<.001	<.001	3	3
UCEC	NAA35 →	+0.592	+2.136	<.001	<.001	3	3
UCEC	UTP11 →	+0.405	+2.914	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,146 associations by consensus.

BCAS2 by GTF3C2 expression — UCEC

Explore this box plot interactively →