GTF3C2

Across TCGA cell cohorts, GTF3C2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,750 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GTF3C2-associated GO terms across cancer lineages are Regulation of mRNA catabolic process, Promoter clearance during DNA-templated transcription, and RNA polymerase II promoter clearance. Each is linked with GTF3C2 in more than 13 cancer types. Because this analysis shows association rather than direction, both GTF3C2-to-partner and partner-to-GTF3C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA catabolic process grouped by GTF3C2-low versus GTF3C2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C2→partner) and Y-score (partner→GTF3C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of mRNA catabolic process →	+0.071	+0.954	<.001	<.001	3	14
SOFT_TISSUE	Promoter clearance during DNA-templated transcription →	+0.149	+0.682	<.001	<.001	3	14
SOFT_TISSUE	RNA polymerase II promoter clearance →	+0.149	+0.682	<.001	<.001	3	14
BONE	Pre-mRNA catabolic process →	+0.245	+0.710	<.001	<.001	3	14
BONE	Regulation of transcription by RNA polymerase I →	+0.109	+0.644	<.001	<.001	3	13
BONE	Nucleic acid transport →	+0.116	+0.698	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,750 associations by consensus.

Regulation of mRNA catabolic process by GTF3C2 expression — SOFT_TISSUE

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