GTF3C1

Across TCGA patient cohorts, GTF3C1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,292 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF3C1-associated genes across cancer lineages are KIF22, RMI2, and SUV39H1. Each is linked with GTF3C1 in more than 8 cancer types. Because this analysis shows association rather than direction, both GTF3C1-to-partner and partner-to-GTF3C1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF3C1 versus KIF22 in LSCC, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C1→partner) and Y-score (partner→GTF3C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KIF22 →	+0.820	+0.392	<.001	<.001	3	9
LSCC	RMI2 →	+0.768	+0.263	<.001	<.001	3	8
LSCC	SUV39H1 →	+0.594	+0.398	<.001	<.001	3	7
LSCC	CCNF →	+0.641	+0.252	<.001	<.001	3	7
BRCA	PLK1 →	+0.998	+0.260	<.001	<.001	3	7
UCEC	SOX12 →	+1.099	+0.266	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,292 associations by consensus.

GTF3C1 vs KIF22 — LSCC

Explore this scatter interactively →