GTF3C1

Across TCGA cell cohorts, GTF3C1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,225 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GTF3C1-associated GO terms across cancer lineages are Regulation of transcription of nucleolar large rRNA by RNA polymerase I, Regulation of chromatin organization, and mRNA transport. Each is linked with GTF3C1 in more than 14 cancer types. Because this analysis shows association rather than direction, both GTF3C1-to-partner and partner-to-GTF3C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription of nucleolar large rRNA by RNA polymerase I grouped by GTF3C1-low versus GTF3C1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C1→partner) and Y-score (partner→GTF3C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.122	+0.516	.002	.005	3	15
LUNG_SCLC	Regulation of chromatin organization →	+0.120	+0.551	<.001	.003	2	15
OESOPHAGUS	mRNA transport →	+0.142	+0.685	<.001	<.001	3	14
STOMACH	RNA export from nucleus →	+0.104	+0.727	<.001	<.001	3	14
STOMACH	tRNA transcription →	+0.159	+0.899	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.183	+1.069	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,225 associations by consensus.

Regulation of transcription of nucleolar large rRNA by RNA polymerase I by GTF3C1 expression — BONE

Explore this box plot interactively →