GTF3AP6

Across TCGA pan-cancer cohorts, GTF3AP6 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated GTF3AP6 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher GTF3AP6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GTF3AP6 expression acts as an unfavorable survival marker, although some lineages such as UCS show a favorable association.

KICH, TGCT, and UCS are the cancer types where GTF3AP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.082	0.877	<.001	78	view →
TGCT	OS	Tertile	II,III,IV	0.501	0.996	<.001	72	view →
UCS	DFS	Tertile	III,IV	0.774	0.238	.014	48	view →
KIRC	DFS	Tertile	All	0.281	0.642	.012	18	view →
ESCA	DFS	Tertile	All	0.243	0.771	.020	18	view →
CESC	DFS	Tertile	All	0.100	0.545	.024	18	view →
READ	OS	Tertile	IV	0.468	0.958	.002	14	view →
LAML	DFS	Median	All	0.454	0.685	.023	12	view →
SKCM	OS	Tertile	IV	0.247	0.721	.038	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

GTF3AP6–KICH (OS)

Open the KICH breakdown →