general transcription factor IIIA pseudogene 1Genealiases: []
Q-omics provides the consensus-scored GTF3AP1 profile across patient tissues and cancer cell-line models. GTF3AP1 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in STAD. Among the 18 cancer types available for tumor–normal comparison, GTF3AP1 is differentially expressed in 4, with the highest sampling consensus in HNSC. Additionally, GTF3AP1 RNA expression shows 6,605 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight STAD, HNSC, and THYM as cancer lineages where GTF3AP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GTF3AP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GTF3AP1 survival associations across molecular data types. GTF3AP1 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GTF3AP1 RNA expression–survival associations across cancer types. High GTF3AP1 expression shows unfavorable associations in STAD, OV, KIRC, TGCT and ESCA, but favorable associations in BLCA. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify STAD as the clearest survival context for GTF3AP1 RNA expression.
This table summarizes GTF3AP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for GTF3AP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GTF3AP1 shows higher tumor expression in HNSC, COAD, READ and LUSC. The HNSC box plot shows higher GTF3AP1 RNA expression in tumor versus normal tissue (log2 FC = +0.022, t-test p = .001).
This table shows molecular features associated with GTF3AP1 in patient tissues and cancer cell lines. In patient samples, GTF3AP1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
