GTF2IRD2B

Across TCGA cell cohorts, GTF2IRD2B mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GTF2IRD2B-associated genes across cancer lineages are SLC32A1, IFNG, and C16orf92. Each is linked with GTF2IRD2B in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2IRD2B-to-partner and partner-to-GTF2IRD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC32A1 grouped by GTF2IRD2B-low versus GTF2IRD2B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2IRD2B→partner) and Y-score (partner→GTF2IRD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLC32A1 →	+0.706	+3.901	<.001	.006	3	1
BLOOD_Leukemia	IFNG →	+0.135	+4.567	.003	.001	3	1
BLOOD_Leukemia	C16orf92 →	+0.190	+4.037	<.001	.004	3	1
BLOOD_Leukemia	PRND →	+0.005	+3.874	.005	.005	3	1
BLOOD_Leukemia	SFT2D3 →	+0.581	+4.450	<.001	.001	3	1
BLOOD_Leukemia	C2orf73 →	+0.052	+4.450	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

SLC32A1 by GTF2IRD2B expression — BLOOD_Leukemia

Explore this box plot interactively →