GTF2IRD1P1

Across TCGA patient cohorts, GTF2IRD1P1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTF2IRD1P1-associated genes across cancer lineages are CD8+ naive T-cells, Basophils, and Epithelial cells. Each is linked with GTF2IRD1P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2IRD1P1-to-partner and partner-to-GTF2IRD1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by GTF2IRD1P1-low versus GTF2IRD1P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2IRD1P1→partner) and Y-score (partner→GTF2IRD1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.036	+3.042	.019	.018	3	1
UCEC	Basophils →	+0.227	+3.000	.021	.037	2	1
UCEC	Epithelial cells →	-0.118	-3.000	.004	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ naive T-cells by GTF2IRD1P1 expression — UCEC

Explore this box plot interactively →