GTF2IP6

Across TCGA patient cohorts, GTF2IP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,643 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GTF2IP6-associated GO terms across cancer lineages are Positive regulation of chromosome organization, Protein localization to chromosome, centromeric region, and Regulation of cell cycle checkpoint. Each is linked with GTF2IP6 in more than 11 cancer types. Because this analysis shows association rather than direction, both GTF2IP6-to-partner and partner-to-GTF2IP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome organization grouped by GTF2IP6-low versus GTF2IP6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2IP6→partner) and Y-score (partner→GTF2IP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of chromosome organization →	+0.094	+0.447	<.001	<.001	3	12
STAD	Protein localization to chromosome, centromeric region →	+0.079	+0.383	<.001	<.001	3	12
STAD	Regulation of cell cycle checkpoint →	+0.075	+0.322	<.001	<.001	3	11
STAD	Protein localization to condensed chromosome →	+0.086	+0.310	<.001	<.001	3	11
STAD	Positive regulation of chromosome separation →	+0.104	+0.330	<.001	<.001	3	11
ESCA	Metaphase chromosome alignment →	+0.097	+0.906	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,643 associations by consensus.

Positive regulation of chromosome organization by GTF2IP6 expression — STAD

Explore this box plot interactively →