GTF2IP20

Across TCGA pan-cancer cohorts, GTF2IP20 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated GTF2IP20 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher GTF2IP20 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GTF2IP20 expression acts as an unfavorable survival marker, although some lineages such as PAAD and UCS show a favorable association.

KIRC, PAAD, and UCS are the cancer types where GTF2IP20 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.449	0.716	<.001	117	view →
PAAD	OS	Quartile	All	0.562	0.219	<.001	46	view →
UCS	DFS	Median	III,IV	0.559	0.283	.016	46	view →
BLCA	OS	Quartile	All	0.666	0.458	<.001	41	view →
COAD	OS	Quartile	All	0.671	0.884	.004	40	view →
MESO	OS	Median	II,III,IV	0.494	0.292	.006	33	view →
UVM	DFS	Quartile	III,IV	0.184	0.826	.001	33	view →
STAD	OS	Tertile	III,IV	0.682	0.349	.015	21	view →
LGG	DFS	Quartile	All	0.239	0.441	<.001	18	view →
PRAD	DFS	Median	All	0.680	0.875	<.001	14	view →
KICH	OS	Quartile	III,IV	0.214	0.895	.017	13	view →
THYM	OS	Median	II,III,IV	0.876	1.000	.004	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

GTF2IP20–KIRC (DFS)

Open the KIRC breakdown →