GTF2I

Across TCGA patient cohorts, GTF2I RNA expression is significantly associated with the protein abundance of many other proteins, with 16,623 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GTF2I-associated proteins across cancer lineages are TRRAP, BAZ1B, and RSBN1L. Each is linked with GTF2I in more than 5 cancer types. Because this analysis shows association rather than direction, both GTF2I-to-partner and partner-to-GTF2I results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF2I versus TRRAP in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2I→partner) and Y-score (partner→GTF2I) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TRRAP →	+0.193	+0.420	<.001	<.001	3	6
GBM	BAZ1B →	+0.312	+0.367	.001	.001	3	6
HNSC	RSBN1L →	+0.257	+0.408	<.001	<.001	3	6
HNSC	MEPCE →	+0.285	+0.440	.001	<.001	3	6
CCRCC	ARHGEF5 →	+0.394	+0.436	<.001	<.001	3	5
LSCC	PUS7 →	+0.439	+0.470	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,623 associations by consensus.

GTF2I vs TRRAP — HNSC

Explore this scatter interactively →