Across TCGA patient cohorts, GTF2H4 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,807 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF2H4-associated proteins across cancer lineages are SF3B3, SNRPD2, and CDC73. Each is linked with GTF2H4 in more than 4 cancer types. Because this analysis shows association rather than direction, both GTF2H4-to-partner and partner-to-GTF2H4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H4→partner) and Y-score (partner→GTF2H4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SF3B3 →	+0.301	+0.174	<.001	<.001	3	5
LSCC	SNRPD2 →	+0.301	+0.165	<.001	<.001	3	5
LSCC	CDC73 →	+0.371	+0.161	<.001	<.001	3	4
GBM	PRPF6 →	+0.269	+0.163	.006	.008	3	4
LSCC	USP39 →	+0.452	+0.162	<.001	<.001	3	4
LSCC	ADNP →	+0.461	+0.171	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,807 associations by consensus.

Exploration

GTF2H4 survival (RNA) · tumor vs normal (RNA) · all GTF2H4 data types