Across TCGA patient cohorts, GTF2H4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,174 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF2H4-associated genes across cancer lineages are TMEM97, AUNIP, and MTFR2. Each is linked with GTF2H4 in more than 4 cancer types. Because this analysis shows association rather than direction, both GTF2H4-to-partner and partner-to-GTF2H4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H4→partner) and Y-score (partner→GTF2H4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TMEM97 →	+1.078	+0.225	.001	<.001	3	5
LSCC	AUNIP →	+0.835	+0.291	<.001	<.001	3	5
LSCC	MTFR2 →	+0.790	+0.322	<.001	<.001	3	5
LSCC	MCM6 →	+0.743	+0.270	<.001	<.001	3	5
HNSC	GTF2H1 →	+0.382	+0.180	<.001	<.001	3	4
HNSC	PSMA1 →	+1.022	+0.217	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,174 associations by consensus.

Exploration

GTF2H4 survival (RNA) · tumor vs normal (RNA) · all GTF2H4 data types