Across TCGA cell cohorts, GTF2H4 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GTF2H4-associated genes across cancer lineages are PRG3 and TMCO5A. Each is linked with GTF2H4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2H4-to-partner and partner-to-GTF2H4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H4→partner) and Y-score (partner→GTF2H4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PRG3 →	+0.029	+5.415	<.001	.004	3	1
LARGE_INTESTINE	TMCO5A →	+0.026	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

GTF2H4 survival (RNA) · tumor vs normal (RNA) · all GTF2H4 data types