Across TCGA pan-cancer cohorts, GTF2H2C Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated GTF2H2C data layer compared with 22 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher GTF2H2C Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GTF2H2C expression acts as an unfavorable survival marker.

LGG are the cancer types where GTF2H2C Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Median	All	0.132	0.830	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: GTF2H2C tumor-vs-normal RNA expression · all GTF2H2C data types