Across TCGA patient cohorts, GTF2H2C protein abundance is significantly associated with the RNA expression of many other genes, with 3,072 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF2H2C-associated genes across cancer lineages are RPS16, RCN2, and LRPPRC. Each is linked with GTF2H2C in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2H2C-to-partner and partner-to-GTF2H2C results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H2C→partner) and Y-score (partner→GTF2H2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPS16 →	+0.995	+1.571	<.001	.005	3	2
LUAD	RCN2 →	+0.541	+1.874	.007	.006	3	2
LUAD	LRPPRC →	+0.486	+1.197	.005	.003	3	2
LSCC	SAAL1 →	+0.619	+0.397	<.001	<.001	3	2
LUAD	GNG7 →	-0.857	-1.637	<.001	.004	3	2
BRCA	CRAMP1 →	-0.984	-0.513	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,072 associations by consensus.

Exploration

GTF2H2C survival (RNA) · tumor vs normal (RNA) · all GTF2H2C data types