GTF2H2C

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GTF2H2C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,084 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GTF2H2C-associated GO terms across cancer lineages are Positive regulation of rRNA processing, Regulation of rRNA processing, and Regulation of mononuclear cell proliferation. Each is linked with GTF2H2C in more than 17 cancer types. Because this analysis shows association rather than direction, both GTF2H2C-to-partner and partner-to-GTF2H2C results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H2C→partner) and Y-score (partner→GTF2H2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTPositive regulation of rRNA processing →+0.156+1.187<.001.001318
LUNG_SCLCRegulation of rRNA processing →+0.115+0.764<.001.001314
LIVERRegulation of mononuclear cell proliferation →-0.104-0.848.002.006314
LIVERRNA modification →+0.051+0.700.001<.001314
UPPER_AERODIGESTIVE_TRACTDNA replication initiation →+0.170+1.469<.001<.001314
UPPER_AERODIGESTIVE_TRACTRegulation of centriole replication →+0.106+1.258<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,084 associations by consensus.

Exploration