Across TCGA cell cohorts, GTF2H2C mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GTF2H2C-associated genes across cancer lineages are C1QTNF7 and OR52K1. Each is linked with GTF2H2C in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2H2C-to-partner and partner-to-GTF2H2C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H2C→partner) and Y-score (partner→GTF2H2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C1QTNF7 →	+0.112	+4.523	<.001	.001	3	1
LARGE_INTESTINE	OR52K1 →	+0.012	+3.632	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

GTF2H2C survival (RNA) · tumor vs normal (RNA) · all GTF2H2C data types